Tinkle, C. et al., “Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma.” (2015)

Treatment Use

Mobetron

Cancer Indication

Sarcoma

Number of Patients

26

Summary/Conclusion

This study demonstrates that incorporation of IORT as a component of multimodality management of patients with locally recurrent ESTS achieves high rates of local control and limb salvage with acceptable treatment morbidity and suggests that prior EBRT does not significantly influence disease control or toxicity. This technique offers a method of delivering focal therapy to achieve local control for the majority of patients who otherwise may require more radical surgical procedures.

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2014 SICPRE Congress Best Abstracts – Aesthetic Evaluation in Oncoplastic and Conservative Breast Surgery: A Comparative Analysis

Treatment Use

Electron IORT

Cancer Indication

Breast (Single-Fraction APBI)

Number of Patients

107

Summary/Conclusion

Background In conservative breast surgery, the achievement of a satisfactory cosmetic result could be challenging; oncoplastic techniques may be helpful in many cases. A comparative analysis was performed among 3 groups of patients undergoing oncoplastic techniques plus external radiation therapy or intraoperative radiotherapy (IORT) and breast conservative surgery plus external radiation therapy; long-term oncologic results … Continued

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Phillippson, C. et al., “Early Invasive Cancer and Partial Intraoperative Electron Radiation Therapy of the Breast: Experience of the Jules Bordet Institute.” (2014)

Treatment Use

Mobetron

Cancer Indication

Breast (Single-Fraction APBI)

Number of Patients

200

Summary/Conclusion

The preoperative diagnostic work-up must be comprehensive and the selection process must be rigorous for this therapeutic approach reserved for small ductal unifocal cancers. After 23.3 months median follow-up, the clinical results of IOERT for selected patients are encouraging for locoregional recurrence rate and toxicity rates. The satisfaction of our patients in terms of quality of life was extremely high.

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Paly, J.J. et al., “Outcomes in a Multi-Institutional Cohort of Patients Treated with Intraoperative Radiation Therapy for Advanced or Recurrent Renal Cell Carcinoma.” (2014)

Treatment Use

Electron IORT

Cancer Indication

Genitourinary

Number of Patients

98

Summary/Conclusion

The outcomes for patients receiving IOERT in the setting of local recurrence compare favorably to similar cohorts treated by local resection alone suggesting the potential for improved DFS with IORT.

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