Paly, J.J. et al., “Outcomes in a Multi-Institutional Cohort of Patients Treated with Intraoperative Radiation Therapy for Advanced or Recurrent Renal Cell Carcinoma.” (2014)

Treatment Use

Electron IORT

Cancer Indication

Genitourinary

Number of Patients

98

Summary/Conclusion

The outcomes for patients receiving IOERT in the setting of local recurrence compare favorably to similar cohorts treated by local resection alone suggesting the potential for improved DFS with IORT.

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Hallemeier, C et al., “Long-Term Outcomes after Maximum Surgical Resection and IOERT for Locoregionally (LR) Recurrent or Locoregionally (LR) Advanced Primary Renal Cell Cancer (RCC).” (2011)

Treatment Use

Electron IORT

Cancer Indication

Genitourinary

Number of Patients

22

Summary/Conclusion

In patients with LR recurrent or LR advanced primary RCC, a multimodality approach of perioperative EBRT, maximum surgical resection and IOERT yielded encouraging results…With mature follow-up, this treatment approach was associated with a low rate of LR recurrence, acceptable toxicity, and long-term survival in a significant number of patients.

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