Summary/Conclusion
From this joint analysis emerges the fact that preoperative radiotherapy increases the effects of IORT in terms of local control and overall survival.
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January 1, 2008
Kondo, T. et al., “Intraoperative Radiotherapy Combined with Posterior Decompression and Stabilization for Non-Ambulatory Paralytic Patients due to Spinal Metastasis.” (2008)
Summary/Conclusion
IORT for spinal cord compression caused by metastatic spinal tumors achieved a good post-operative ambulatory rate (80%) regardless of the cancer type or presence or absence of previous EBRT, thereby revealing its usefulness.
Read MoreJanuary 1, 2007
Jaske G., et al., “IORT and External Beam Irradiation (EBI) in Clinical Stage I-II NSCLC Patients with Severely Compromised Pulmonary Function: A 52-Patient Single-institutional Experience.” (2007)
Summary/Conclusion
The use of IORT to deliver high single fraction doses precisely limited to the tumor and the possibility to tailor subsequent moderate-dose EBRT according to the spread of the disease offers a potentially curative therapy in patients who are unable to undergo radical surgery or radical EBRT due to their severe functional impairment.
Read MoreDecember 27, 2006
Zhou, G. et al., “Analysis of the Long-Term Effect of Intraoperative Radiotherapy (IORT) for Non-Small Cell Lung Cancer (NSCLC).” (2007)
Summary/Conclusion
IORT plus postoperative EBRT can enhance the local control rate of NSCLC patients and reduce recurrences.
Read MoreJanuary 18, 2006
Krempien, R. et al., “Intraoperative Electron-Beam Therapy for Primary and Recurrent Retroperitoneal Soft-Tissue Sarcoma.” (2006)
Summary/Conclusion
In selected patients, IOERT results in excellent local control and survival, with acceptable morbidity….IOERT in combination with EBRT seems to be able to compensate for minimal residual disease.
Read MoreJanuary 1, 2006
Lemanski, C. et al.,“Intraoperative Radiotherapy Given As A Boost For Early Breast Cancer: Long-term Clinical And Cosmetic Results.” (2006)
Summary/Conclusion
Our results confirm that IORT given as a boost after breast-conserving surgery is a reliable alternative to conventional postoperative fractionated boost radiation.
Read MoreDecember 27, 2005
Reitsamer, R. et al., “The Salzburg concept of intraoperative radiotherapy for breast cancer: Results and considerations.” (2006)
Summary/Conclusion
Immediate IORT-boost and whole breast irradiation yields excellent local control at 5 years, and was associated with a statistically significant decreased rate of IBTR compared with a similar cohort of patients treated with whole breast irradiation and conventional electron boost.
Read MoreJanuary 1, 2005
Willett, C. et al., “Long-term Results of IOERT for Patients with Unresectable Pancreatic Cancer.” (2005)
Summary/Conclusion
A treatment strategy employing IOERT has resulted in long-term survival in 8 of 150 patients with unresectable pancreatic cancer.
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