Summary/Conclusion
IORT results in effective local disease control at acceptable levels of toxicity and should be considered for patients with primary or recurrent cancer of the parotid gland.
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February 11, 2011
Hallemeier, C et al., “Long-Term Outcomes after Maximum Surgical Resection and IOERT for Locoregionally (LR) Recurrent or Locoregionally (LR) Advanced Primary Renal Cell Cancer (RCC).” (2011)
Summary/Conclusion
In patients with LR recurrent or LR advanced primary RCC, a multimodality approach of perioperative EBRT, maximum surgical resection and IOERT yielded encouraging results…With mature follow-up, this treatment approach was associated with a low rate of LR recurrence, acceptable toxicity, and long-term survival in a significant number of patients.
Read MoreOctober 29, 2009
Haddock, M. et al., “Combined Modality Therapy Including Intraoperative Electron Irradiation for Locally Recurrent Colorectal Cancer.” (2010)
Summary/Conclusion
Long-term survival and disease control was achievable in patients with locally recurrent colorectal cancer…curative- intent, combined-modality therapy that includes IOERT is warranted in this high-risk population.
Read MoreMarch 7, 2009
Kusters, M. et al., “Patterns of Local Recurrence in Locally Advanced Rectal Cancer (LARC) After Intraoperative Radiotherapy Containing Multimodality Treatment.” (2009)
Summary/Conclusion
Multimodality treatment is effective in prevention of local recurrence in LARC. IORT application to the area most at risk is feasible and seems effective in the prevention of local recurrence.
Read MoreAugust 30, 2008
Valentini, V. et al., “IORT in Pancreatic Cancer: Joint Analysis of the ISIORT European Experience.” (2009)
Summary/Conclusion
From this joint analysis emerges the fact that preoperative radiotherapy increases the effects of IORT in terms of local control and overall survival.
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