Summary/Conclusion
IORT for spinal cord compression caused by metastatic spinal tumors achieved a good post-operative ambulatory rate (80%) regardless of the cancer type or presence or absence of previous EBRT, thereby revealing its usefulness.
Read MoreSummary/Conclusion
The introduction of IORT has allowed a selective treatment approach to locally advanced primary and recurrent neoplasms, which traditionally would have been deemed unresectable. Using IORT, extended resections may be avoided in selected high risk patients with low risk of local recurrence and minimal morbidity.
Read MoreSummary/Conclusion
IORT at the time of primary resection offers effective local control in patients with high-risk neuroblastoma. Compared to historical controls, IORT achieved comparable control and survival rates while avoiding many side effects associated with external beam radiotherapy in young children.
Read MoreSummary/Conclusion
The use of IORT to deliver high single fraction doses precisely limited to the tumor and the possibility to tailor subsequent moderate-dose EBRT according to the spread of the disease offers a potentially curative therapy in patients who are unable to undergo radical surgery or radical EBRT due to their severe functional impairment.
Read MoreSummary/Conclusion
IORT plus postoperative EBRT can enhance the local control rate of NSCLC patients and reduce recurrences.
Read More