In vivo dosimetry with MOSFETs and GAFCHROMIC films during electron IORT for Accelerated Partial Breast Irradiation

Treatment Use

Electron IORT

Mobetron

Cancer Indication

Breast (Single-Fraction APBI)

Number of Patients

47

Summary/Conclusion

Authors AnnaPetoukhova, IrisRüssel, JulienneNijst-Brouwers, Kovan Wingerden, Jaapvan Egmond, DaphneJacobs, AndreasMarinelli, Joostvan der Sijp, PeterKoper, HenkStruikmans  Purpose The purpose of this study was to compare the delivered dose to the expected intraoperative radiation therapy (IORT) dose with in vivo dosimetry. For IORT using electrons in accelerated partial breast irradiation, this is especially relevant since a high dose is delivered in a single fraction. Methods For … Continued

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S. Takanen – Breast cancer electron intraoperative radiotherapy

Treatment Use

Electron IORT

Cancer Indication

Breast (Single-Fraction APBI)

Number of Patients

758

Summary/Conclusion

In our current practice we consider the following preoperative factors to select patients suitable for IORT: age > 50 years, absence of lobular histology, tumor size ≤ 2 cm, pN0 or pNmic, according to APBI consensus statement, including also ki67 ≤ 20%, non triple negative receptor status and G1-G2

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The Role of Intraoperative Radiation Therapy in the Management of Recurrent and Locally Advanced Gynecologic Cancers

Treatment Use

Electron IORT

Cancer Indication

Gynecological

Number of Patients

Summary/Conclusion

For patients with locally advanced primary or recurrent gynecologic cancers, prognosis is poor. Doses of EBRT required to treat either gross or microscopic disease in patients previously irradiated or treated surgically exceed doses that are tolerated by normal anatomic structures …

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