Summary/Conclusion
For upper-extremity sarcoma, treatment including IOERT was associated with excellent LC, limb preservation and survival.
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December 16, 2011
Zhang, Q. et al., “Adjuvant Chemoradiotherapy with or without Intraoperative Radiotherapy for the Treatment of Resectable Locally Advanced Gastric Adenocarcinoma.” (2011)
Summary/Conclusion
IOERT followed by adjuvant chemoradiotherapy after D2 gastrectomy is an efficacious and well tolerated treatment for patients with locally advanced gastric adenocarcinoma. It significantly improves locoregional control and marginally improves disease free survival.
Read MoreAugust 8, 2011
Leonardi, M.C. et al., “How do the ASTRO Consensus Statement Guidelines for the Application of Accelerated Partial Breast Irradiation Fit Intraoperative Radiotherapy? A Retrospective Analysis of Patients Treated at the European Institute of Oncology.” (2012)
Summary/Conclusion
The 5-year rate of ipsilateral breast recurrence for ASTRO suitable, cautionary and unsuitable groups were 1.5%, 4.4% and 8.8% (p = 0.0003)…the ASTRO recommendations offer useful guidance to judge the appropriateness of APBI using ELIOT.
Read MoreJuly 6, 2011
Barney B., et al., “IOERT in the Management of Recurrent Ovarian Malignancies.” (2011)
Summary/Conclusion
Combined modality therapy with EBRT, surgery and IOERT is an option for the treatment of localized recurrent ovarian cancer, with acceptable rates of in-field failure and toxicity. Durable disease control is possible in select women treated with this regimen.
Read MoreJune 15, 2011
Zeidan, Y. et al., “Intraoperative radiation therapy for advanced cervical metastasis: A Single-Institution Experience.” (2011)
Summary/Conclusion
IORT results in effective local disease control at acceptable levels of toxicity. Our results support the
initiation of a phase III trial comparing outcomes for patients with cervical metastasis treated with or without IORT.